Spinal Muscular Atrophy In Children: Know About The Oral Drug In SMA, Expert Speaks, Watch Video

Spinal muscular atrophy (SMA) describes a group of disorders associated with spinal motor neuron loss. The different forms of SMA are associated with numerous gene mutations and significant phenotypic variability. SMA is usually categorized by a pattern of weakness whether predominantly proximal or distal and mode of inheritance. Spinal muscular atrophy type 0 is evident before birth and is the rarest and most severe form of the condition. Affected infants move less in the womb, and as a result, they are often born with joint deformities (contractures). They have extremely weak muscle tone (hypotonia) at birth.