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Metabolic Syndrome: Around 40 percent of Americans currently have metabolic syndrome, which is the term for a group of risk factors that raise their risk of developing serious health conditions such as diabetes, stroke, and heart disease. Those who have metabolic syndrome have three or more of the following risk factors: high blood pressure, low levels of HDL cholesterol, extra fat around the waist, high triglycerides, and high blood sugar levels. Watch Video.