Jaundice is a pathological condition that arises due to over accumulation of bilirubin in the liver. When the liver fails to metabolise and excrete bilirubin (as bile) out of the body, it gets deposited in the liver. Such a pathological situation is manifested as yellowing of eyes and skin. In severe cases, the eyes become brown and urine turns dark. Fatigue and vomiting are the other symptoms of this disorder. Jaundice is an indicator of several other liver diseases like liver cirrhosis, cancer, hepatitis and hemolytic anemia. Medicinal overdose and alcohol abuse also contribute to the development of jaundice. This pathological condition is generally reflected in liver function tests (amounts of liver enzymes gets altered). In severe cases, liver imaging tests and sometimes biopsies are also recommended.
