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Understanding Drug-Resistant Epilepsy: Symptoms And Surgery

Here are five stigmas related to epilepsy and the treatment.

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Written By: Tavishi Dogra | Updated: March 7, 2025, 5:38 PM

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Medically Verified By: Dr Malla Devi Vinaya, Speciality - Internal Medicine, Apollo Clinic Kondapur

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What Are The Symptoms Of Drug-resistant Epilepsy?

People with drug resistant epilepsy often experience frequent medication changes, taking more than two medications at the same time, experiencing unwanted side-effects of medication and having more frequent visits to the doctor or hospital.

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When Is Surgery Recommended For Such Patients?

There are four conditions when the surgery is recommended, first is when the patient's seizures is not controlled by the medications, second is when seizures start in a small, well-defined area of the brain and the third is when the surgery won't affect vital functions like speech, language, movement, vision, or hearing. Also Read - Autism may raise risk of psychosis and schizophrenia symptoms, study warns

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What Are The Different Surgical Interventions That Can Be Taken Up?

Different surgical interventions included removing a small part of the brain from where the seizures starts or removing a brain leision that causes seizures. Disconnecting parts of the brain and implanting devices such as Vagus nerve stimulation (VNS), Responsive neurostimulation (RNS) and Deep brain stimulation (DBS).

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Can Drug Resistance Persist Post Surgery?

Yes, drug resistance can persist post the epileptic surgery. It is due to some patients who tend to respond initially to medication, but develop drug resistance over time. Whereas in some cases drug resistance can be present from the start, so some patients are resistant to antiseizure drugs from the beginning.