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Prenatal Exposure To Chemicals Liked To Rising Liver Disease In Children: Some Facts You Should Know

Currently, there is no cure for fatty liver disease. Below are some lesser-known facts about pediatric liver disease.

Written by Longjam Dineshwori | Updated : July 9, 2022 8:31 PM IST


Liver Disease On The Rise Among Children

Cases of non-alcoholic fatty liver disease in children are rising worldwide. Prenatal exposure to endocrine-disrupting chemicals in consumer and industrial products may be one of the main reasons behind it, Mount Sinai researchers have suggested. Examples of endocrine-disrupting chemicals include PFAS (used in nonstick cookware and food packaging), pesticides, plasticizers (phenols, phthalates), PBDEs (used as flame retardants in furniture and infant products), and parabens. These chemicals interfere with hormones and metabolic systems in the body. Several studies have shown that exposures to these chemicals can lead to liver injury and non-alcoholic fatty liver disease. The Mount Sinai study is the first study on the association of prenatal mixture exposures to these chemicals and non-alcoholic fatty liver disease. The findings were published in JAMA Network Open in July. Damaskini Valvi, senior author of the study, commented, “We are all daily exposed to these chemicals through the food we eat, the water we drink, and the use of consumer products. This is a serious public health problem.” Below are some lesser-known facts about pediatric liver disease:


Fatty Liver May Be Due To Genetic Mutations

Not all fatty liver diseases are related to obesity. Certain genetic mutations can lead to fatty liver (mainly related to cholesterol homeostasis).


NAFLD Associated With Type 2 Diabetes

A study, published in Clinical Gastroenterology and Hepatology, suggested that pediatric liver disease can lead to type 2 diabetes.