Is Chemotherapy Mandatory After Surgery For Colon Cancer?

Colon cancer surgery A vast majority of patients undergo surgery for colon cancer if the tumour has not spread to other parts of the body. This is done to cure. After around a week, the histopathology (biopsy) report is in. The question is whether chemotherapy is required or whether observation with regular check-ups is enough. The basic rule of thumb is that chemotherapy is suggested if the chances of tumour recurrence are relatively high, based on scientific evidence.Routine colonoscopy Most patients in India will require chemotherapy since the stage at which the cancer is detected is usually advanced. Very early-stage tumours are mainly detected on routine colonoscopy (general check-up without symptoms) and are incidentally diagnosed. Once a patient develops significant symptoms, it is usually at a stage which requires chemotherapy.Chemotherapy after surgery Patients in which the tumour has penetrated the wall of the colon or if lymph nodes are involved will require chemotherapy. Poorly differentiated tumours should also be considered for chemotherapy. If the report reveals stage 2 disease (pT3N0) with no other poor prognostic features, an MSI (Microsatellite Instability test) is advised. This helps in the decision about the benefit of adjuvant chemotherapy.In short There are instances when chemotherapy may not be required, but it is uncommon. Chemotherapy may not be advised if the tumour stage is very early, with minimal symptoms. Another reason for not advising chemotherapy is if the patient's general condition is unfit to tolerate chemotherapy.To conclude Your oncologist is the best person to decide on treatment options in consultation with a multidisciplinary tumour board. Organ-based disease management clinical groups ensure the best possible outcomes for patients.