Chemotherapy After Surgery
Patients in which the tumour has penetrated the wall of the colon or if lymph nodes are involved will require chemotherapy. Poorly differentiated tumours should also be considered for chemotherapy. If the report reveals stage 2 disease (pT3N0) with no other poor prognostic features, an MSI (Microsatellite Instability test) is advised. This helps in the decision about the benefit of adjuvant chemotherapy.