Written By: Bhavyajyoti Chilukoti | Published : May 8, 2015 1:30 PM IST
Thalassemia is a blood disorder in which there is an insufficient production of the red blood cells due to a defective haemoglobin chain. The normal lifespan of RBCs is 120 days; however, in case of thalassemia the life span of these cells is less than normal. This is the reason, why thalassemic patients need to undergo a frequent blood transfusion.
Statistics in India
According to the Indian Red Cross Society, around 1, 00, 000 people are suffering from thalassemia major and more than 8, 000 thalassemic children are born every year. However, there are several cases of thalassemia that are not reported. Here is why you should get yourself tested for thalassemia, if planning to get hitched?
How is it caused?
It is a genetic condition in which there is a defect in the genes that code for haemoglobin, an oxygen-carrying molecule. Hemoglobin is made up of two chains (alpha and beta). A defect in either of these genes causes abnormal haemoglobin production, which in turn causes RBC destruction.
What is the mode of inheritance?
Also, if your mother or father or both suffer from thalassemia, there is high chance that the gene can be inherited by you. Depending upon the pattern of inheritance, thalassemia is divided into two types
Treatments and complications what you need to know?
The common treatment options in India used to treat thalassemia are
Read about scientists develop a new treatment for thalassemia
But, given the fact that these people have to be on blood transfusion for their entire life, they go through severe pain and trauma. Also, frequent blood transfusion causes iron overload in the body leading to hepatic (liver), cardiac and endrocrinal complications.
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