Researchers have found that Vitamin D and marine omega-3 fatty acids -- also known as fish oil -- are not effective at reducing systemic inflammation. The study published in the journal Clinical Chemistry is an analysis of the Vitamin D and OmegA-3 TriaL (VITAL) by investigators at Brigham and Women's Hospital in the UK. People commonly think that these supplements can prevent inflammatory diseases but when a patient asks their doctor 'Should I take this supplement?' Doctors often don't know what to advise because there haven't been large scale clinical trials. VITAL provides a large dataset to address these questions