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Researchers at the Oxford University Press USA identified 3,621 endometrial cancer survivors using the Utah Population Database. Diagnosis data was available for women aged 18 and over diagnosed with this cancer between 1997 and 2012 in Utah.
The results of the study indicated that approximately 25.7% of cancer survivors were diagnosed with heart diseases five to ten years after cancer diagnosis. Endometrial cancer survivors were 47% more likely to be diagnosed with a disease of the heart between one of five years after cancer diagnosis and 33% more likely to be diagnosed with a disease of the heart between five to ten years after the initial cancer diagnosis.
Researchers observed elevated risk during the one-to-five-year time period for peripheral and vascular atherosclerosis, hypotension, phlebitis, thrombophlebitis, thromboembolism, other circulatory diseases, and other diseases of the veins and lymphatics. Researchers found associations for hypotension, diseases of veins and lymphatics, and other diseases of veins and lymphatics.
Between one to five years after diagnosis, researchers observed increased cardiovascular risks among endometrial cancer survivors for phlebitis, thrombophlebitis and thromboembolism, lymphatic diseases, pulmonary heart disease, and atrial fibrillation. Some elevated risk persisted for cardiovascular diseases at five to ten years.
Compared to the patients who had surgery, those who additionally had radiation therapy and/or chemotherapy were at increased risk for heart and circulatory system disorders between one to five years after cancer diagnosis.
This study suggested that increased monitoring for cardiovascular diseases might be important for endometrial cancer patients for 10 years after cancer diagnosis.
The findings are published in the Journal of the National Cancer Institute.
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