Besides removing those wrinkles and enhancing your beauty botox has also been proven to be effective and safe in treating chronic migraine that affects your daily activities says a new study. Chronic migraine is defined as at least 15 headache attacks per month for more than three months with migraine symptoms on at least eight days every month. The study showed that botox or botulinum toxin injections is superior to inactive placebo for preventive treatment of migraine and that it significantly reduced the frequency of chronic migraine attacks. Botox prevents migraine headaches before they start but takes time to work.