Researchers have identified a stem cell protein that may play an important role in finding cure for blood cancer. The study done on mice suggests a stem cell protein called Asrij is a novel regulator of wild type tumour suppressor p53 stability in hematopoietic stem cells (HSCs). It could help design targeted therapies for myeloproliferative disease a group of slow-growing blood cancers according to researchers including Maneesha S. Inamdar from the Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR) in Bengaluru. We provide a new mouse model resembling myeloproliferative disease and identify a post-translational regulator of wild type p53 essential
