Taking cholesterol-lowering statins significantly reduces the risk of developing depression in patients with heart disease (Myocardial Infarction) according to researchers. Researchers suggest that taking cholesterol lowering statin may help prevent depression. They then followed the 776 patients who were not depressed - 520 who were using statins and 256 who were not - for an additional six years. Of those taking statins 18.5 per cent developed depression compared with 28 per cent of those not on the drugs. As the study progressed the patients on statins became less likely to develop depression and the patients not on statins became even more depressed over time.