Switch to हिंदी

Health, Fitness, Beauty & Diet | Pregnancy & Parenting | Diseases & Home Remedies | TheHealthSite.com

Health, Fitness, Beauty & Diet | Pregnancy & Parenting | Diseases & Home Remedies | TheHealthSite.com

हिंदी
  • Health A-Z
  • Diabetes
  • Diseases
    • Type 1 Diabetes
    • Type 2 Diabetes
    • Cancer
    • Heart Attack
    • Pneumonia
    • Diseases A-Z
  • Diet & Fitness
    • Weight Management
    • Exercise & Body Building
    • Diet & Recipes
    • Yoga
  • Coronavirus
  • News
  • Pregnancy
    • Conceiving
    • Infertility
    • Labour & Delivery
    • Pregnancy week-by-week
    • Breastfeeding
    • Baby Names
  • Beauty
    • Skin
    • Hair
    • Grooming
  • Photos
  • Videos
Home / Health News / Scientists discover new technology to deliver drug to brain injuries

Scientists discover new technology to deliver drug to brain injuries

New technology discovered that delivers drug to brain injuries.

By: Agencies   | | Published: June 29, 2016 6:36 pm
Tags: Brain  Brain health  Brain injury  
brain

Researchers, including one of Indian-origin, have developed a technology that may aid in driving drugs or nanoparticles to injured areas of the brain, leading to new therapeutics for traumatic brain injuries. Current interventions for acute brain injury are aimed at stabilising the patient by reducing intracranial pressure and maintaining blood flow, but there are no approved drugs to stop the cascade of events that cause secondary injury, said lead author Aman Mann, post-doctoral researcher at Sanford Burnham Prebys Medical Discovery Institute (SBP) in the US. The researchers found a peptide sequence of four amino acids, cysteine, alanine, glutamine, and lysine (CAQK), that recognises injured brain tissue. In mouse models of acute brain injury, this CAQK carried the drug-sized molecules and nanoparticles to the damaged areas. Using this peptide to deliver drugs means they could be administered intravenously, but still reach the site of injury in sufficient quantities to have an effect, said Erkki Ruoslahti, Professor at SBP. (Read: Wearing the new neck collar may prevent brain injuries in athletes) Also Read - Beware! Obesity can lead to severe brain pressure disorder

Also Read - Traumatic brain injury can increase risk of Alzheimer's disease: Tips to avoid head injuries



While the initial injury cannot be repaired, the damaging effects of breaking open brain cells and blood vessels that ensue over the following hours and days can be minimised, the researchers said. Our goal was to find an alternative to directly injecting therapeutics into the brain, which is invasive and can add complications. This peptide could be used to deliver treatments that limit the extent of damage, Ruoslahti explained in the paper published in the journal Nature Communications. This peptide could also be used to create tools to identify brain injuries, particularly mild ones, by attaching the peptide to materials that can be detected by medical imaging devices. (Read: Children and young adults take longer to recover from brain injuries) Also Read - New drug-delivery system opens possibilities for treatment of numerous neurological disorders

As the peptide can deliver nanoparticles that can be loaded with large molecules, it could enable enzyme or gene-silencing therapies, Ruoslahti added. The CAQK peptide also binds to components of the meshwork surrounding brain cells called chondroitin sulfate proteoglycans, amounts of which increase following a brain injury. When tested in injured human brain samples, this peptide binding was found to have the same selectivity, the researchers concluded. (Read: A traumatic brain injury can increase your risk of cognitive impairment)

Source: IANS

Photo source: Getty images (Image for representational purpose only)

Published : June 29, 2016 6:36 pm
Read Disclaimer

Viral infections of the brain to be discussed at the Indo-US conference in Kolkata

Viral infections of the brain to be discussed at the Indo-US conference in Kolkata

Did you know that the environment could impact the onset of puberty?

Did you know that the environment could impact the onset of puberty?

Please Wait. Article Loading ....

Coronavirus Updates

Coronavirus Updates

Stay Informed, Be Safe

  • Coronavirus: WHO issues new advisory for COVID-19 patients
  • India’s Covaxin can neutralize UK variant of COVID-19, finds new study
  • COVID-19 vaccination FAQs: All you need to know before you get the jab
  • Increase your omega-3 intake to reduce death risk due to Covid-19
  • COVID-19 Live Updates: Cases in India surge to 10,676,838 while death toll reaches 1,53,587

Health Calculators

BMI Calculator
bmi Calculator
Ideal Body Weight
ideal body weight
Daily Calorie Intake
Daily calorie intake
Calories Burned
calories burned

Related Stories

Traumatic brain injury can put you at high risk of dementia even after 30 years

Traumatic brain injury can put you at high risk of dementia even after 30 years

Traumatic brain injury (TBI) can cause gut dysfunction

Traumatic brain injury (TBI) can cause gut dysfunction

Premature babies with brain injuries more at the risk of mental health issues like substance dependence and depression

Premature babies with brain injuries more at the risk of mental health issues like substance dependence and depression

A brain injury is two times more likely to develop attention problems

A brain injury is two times more likely to develop attention problems

Wearing the new neck collar may prevent brain injuries in athletes

Wearing the new neck collar may prevent brain injuries in athletes

Health News in Hindi

Gall Bladder Surgery: गॉल ब्लैडर सर्जरी के बाद ऐसे करें डायट में बदलाव, करें इन फूड्स का सेवन और इनसे परहेज

सर्वाइकल कैंसर का पता लगाने के लिए महिलाएं हर 3 साल पर जरुर कराएं ये एक टेस्‍ट, पढें एक्‍सपर्ट की सलाह

Omega-3 Fatty Acids: कोवि़ड-19 से मौत का खतरा कम करता है ओमेगा-3 एसिड, इन फूड्स से पूरी हो सकती है इसकी दैनिक ज़रूरत

Blood Test Guideline: ब्लड टेस्ट कराने से पहले कुछ खाना चाहिए या नहीं? पढ़ें ब्लड टेस्ट कराने से पहले की पूरी गाइडलाइन

सीने में दर्द के बाद सौरव गांगुली अस्‍पताल में भर्ती, कुछ दिन पहले कराई थी एंजियोप्‍लास्‍टी

Read All

Recent Posts

  • Coronavirus: WHO issues new advisory for COVID-19 patients
  • Soy Milk vs Almond Milk: Which one is better for your health?
  • Sourav Ganguly hospitalised again because of chest pain: Is this normal after angioplasty?
  • ‘Extremely essential’: Kareena Kapoor Khan on importance of yoga during pregnancy
  • Exposure to antibiotics linked to reduced weight and height in boys: Study

About The health Site

TheHealthSite.com is India's largest health site with more than 40 lakh unique visitors per month. We focus on fitness, beauty, health, pregnancy and more.

Most popular health and wellness website in India in 2012 at the Website of the year awards.

health@corp.india.com
+91 – 22 – 6697 1234
Landline Phone number 91 – 22 – 2490 0302.

ZEE ENTERTAINMENT ENTERPRISES LTD, 18th floor, A-Wing, Marathon Futurex, N. M. Joshi Marg, Lower Parel, Mumbai, Maharashtra 400013.

Useful Links

  • Weight Loss
  • Keto Diet Tips
  • Skin Care Tips
  • Intermittent Fasting
  • Apple Cider Vinegar
  • Ashwagandha
  • Cancer
  • Pneumonia
  • Diarrhoea
  • Dengue
  • Typhoid
  • Tuberculosis
  • Chickenpox
  • Chikungunya
  • Depression
  • Hepatitis
  • Diabetes
  • Type 2 diabetes
  • Arthritis
  • Swine Flu
  • Baby Names
  • Cough and cold
  • Heart Attack
  • Breast Cancer
  • Ebola Virus
  • Dengue
  • Malaria
  • International Yoga Day
  • Hypotension
  • Heart Failure
  • Asthma
  • Brain Tumour
  • Celebrity Fitness
  • Goitre
  • HIV/AIDS

We respect your privacy

  • Disclaimer
  • Privacy Policy
  • Contact Us
  • Author Profiles

Copyright © 2021 Zee Entertainment Enterprises Limited. All rights reserved.