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Home / Health News / Scientists come up with 18k antibiotics combinations to kill e. coli bacteria

Scientists come up with 18k antibiotics combinations to kill e. coli bacteria

A team of researchers tested four-and five-drug combinations and created a total of 18,278 combinations, with different dosages, that could kill E. coli.

By: Sudhakar Jha   | | Published: September 4, 2018 7:00 pm
Tags: Antibiotics  Antibiotics medicine  E.coli bacteria  use of antibiotics  
E.Coli
A research team has discovered antibiotics combinations of four-and five-drug that can effectively kill the harmful bacteria © Shutterstock

In what could be a landmark study, a team of researchers from the University of California, Los Angeles has discovered antibiotics combinations of four-and five-drug that can effectively kill harmful bacteria. Also Read - Exposure to antibiotics linked to reduced weight and height in boys: Study

The study, published in the journal npj Systems Biology and Applications, is now being seen as a major step towards an improved public health care. It has traditionally been believed that a combination of more than two drugs to fight bacteria doesn’t work efficiently. Also Read - Antibiotic resistance looms large; New class of drugs may help fight the challenge



For this study, the team worked with eight antibiotics, and created a total of 18,278 combination with four to five drugs that could kill E. coli. For every combination that the team tested, they first predicted about the potency of all. In the four-drug combinations, 1,676 groupings performed better than they had expected. And in the five-drug combinations, 6,443 groupings were more effective their predictions. Also Read - Are antibiotics safe for teenagers - What to expect?

Pamela Yeh, one of the study’s senior authors, said that her team is offering an alternative that looks very promising. She added that there shouldn’t be a limitation to a single drugs or two-drug combinations in the medical toolbox. And her team is expecting that several of the combinations, or more, would work much better than the existing antibiotics.

Dr. Van Savage, another senior author reportedly said, “I was blown away by how many effective combinations there are as we increased the number of drugs.”

Dr. Elift tekin, lead author of the study added that 2,331 four-drug combinations and 5,199 five-drug combinations were less effective than the researchers expected them to be.

Dr. Yeh concluded that though the results are promising, the drug combinations were tested in only a laboratory setting and there are more tests needed to evaluate their usage on humans. The researchers are also creating an open-access software for their work which they are planning to share with other scientists to work on.

Published : September 4, 2018 7:00 pm
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Health News in Hindi

शिशु को ब्रेस्ट पंप का दूध पिलाना कितना हेल्दी, जानें दूध को स्टोर करने का तरीका, फायदे-नुकसान

केंद्र सरकार ने वैक्सीन की 1 खुराक की कीमत की तय, जानें सरकारी और निजी अस्पतालों में क्या होगी वैक्सीन की कीमत

पिछले एक सप्‍ताह में इन 8 राज्‍यों में फिर से बढ़े कोरोना के मामले, स्थिति से निपटने के लिए उच्‍च स्‍तरीय बैठक, केंद्र ने जारी किया अलर्ट

Bitter Foods Benefits: कड़वी सब्जियां जो सेहत के लिए हैं बेहद हेल्दी, होते हैं गजब के फायदे

सेलेब्रिटी न्यूट्रीशनिस्ट रुजुता दिवेकर से जानिए लंच करने का परफेक्‍ट टाइम, रहेंगे हरदम फिट

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