In a breakthrough Israeli scientists are developing a novel method that would one day help preserve the fertility of boys after undergoing chemotherapy treatment for prepubertal cancer. Aggressive chemotherapy in childhood often results in male testicular damage and consequently jeopardises future fertility. The novel cell-culture system has the potential to change the testicular stem cells into sperm-like cells that may enable future fertility for boys. The findings showed that the presence of spermatogonial cells (SPGCs) in the testes of prepubertal cancer patient boys (PCPBs) can be used to develop future strategies for male fertility preservation. Our results demonstrate for the