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Home / Health News / Scientists are now developing method to preserve fertility in boys with cancer

Scientists are now developing method to preserve fertility in boys with cancer

Aggressive chemotherapy in childhood often results in male testicular damage and consequently jeopardises future fertility.

By: Agencies   | | Published: June 19, 2018 5:47 pm
Tags: Cancer patients  Chemotherapy  Orgasm  Semen  Stem cells  

In a breakthrough, Israeli scientists are developing a novel method that would one day help preserve the fertility of boys after undergoing chemotherapy treatment for prepubertal cancer. Aggressive chemotherapy in childhood often results in male testicular damage and consequently jeopardises future fertility. The novel cell-culture system has the potential to change the testicular stem cells into sperm-like cells that may enable future fertility for boys. Also Read - Small delays in cancer treatment can up death risk by 10%, says study

The findings showed that the presence of spermatogonial cells (SPGCs) in the testes of prepubertal cancer patient boys (PCPBs) can be used to develop future strategies for male fertility preservation. Also Read - Chemotherapy and sex: Is sexual activity safe during cancer treatment?



“Our results demonstrate, for the first time, the presence of biologically active SPGCs in testicular biopsies of chemotherapy-treated PCPBs, and their capacity to develop in vitro to different stages of spermatogenesis, including the generation of sperm-like cells,” said lead researcher Professor Mahmoud Huleihel, from the Ben-Gurion University of the Negev in Beersheba, Israel. Also Read - Breast Cancer Awareness Month: Why chemotherapy causes weight gain?

In the study, published in Stem Cells and Development, seven testicular biopsies were obtained from chemotherapy-treated PCPBs. Read: Nutrients found in red meat can play an important role in improving fertility levels in both men and women.

The researchers were able to cultivate and isolate testicular cells into different stages of development (pre-meiotic, meiotic and post-meiotic cells). Furthermore, they identified sperm-like cells that had developed from testicular cells of a PCPB. Did you know? Malaria affects the reproductive health of both men & women

This study may open the way for new therapeutic strategies for fertility preservation of PCPBs as well as for azoospermic patients, the complete absence of sperm from the fluid ejaculated during orgasm (semen), the Huleihel noted.

Source: IANS
Image Source: Shutterstock

Published : June 19, 2018 5:47 pm
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