Sign In
  • ENG

Salivary gland test might help detect Parkinson's early!

Written by Admin |Published : January 11, 2013 2:31 PM IST

A new research suggests that a person s salivary gland might help diagnose Parkinson s disease! The disease affects people over 50 years of age and the most common symptoms are slowness, restricted motion, muscle stiffness and tremors. There is currently no diagnostic test for Parkinson's disease, says study author Charles Adler, neurologist with Mayo Clinic in Arizona, US.

We have previously shown in autopsies of Parkinson's patients that the abnormal proteins associated with Parkinson's are consistently found in the submandibular saliva glands, found under the lower jaw, adds Adler. Making a diagnosis in living patients is a big step forward in our effort to understand and better treat patients, says Adler, according to a Mayo Clinic statement. The study involved a group of people averaging 68 years who had Parkinson's for an average of 12 years. They had responded to Parkinson's medication and would not have known saliva gland disorders.

Biopsies were taken of two different saliva glands: the submandibular gland and the minor saliva glands in the lower lip.The surgical team was led by Michael Hinni and David Lott, at the Mayo Clinic and the biopsied tissues were tested for evidence of the abnormal Parkinson's protein by study co-author Thomas Beach, with Banner Sun Health Research Institute.

Also Read

More News

This procedure will provide a much more accurate diagnosis of Parkinson's disease than what is now available, Beach says. One of the greatest potential impacts of this finding is on clinical trials, as at the present time some patients entered into Parkinson's clinical trials do not necessarily have Parkinson's disease and this is a big impediment to testing new therapies, Beach says.

The abnormal Parkinson's protein was detected in nine of the 11 patients who had enough tissue to study. Although Parkinson's disease can't be cured, medications may markedly improve symptoms. These findings will be presented at the American Academy of Neurology's annual meeting in San Diego in March.

What is Parkinson's disease?

Parkinson s disease is a neurodegenerative disorder and affects nerve cells which are responsible for motor functions of the body. Parkinson s patients have difficulty in carrying out movements at a normal speed. Hence, they take longer to perform even normal day-to-day activities. Apart from slowness in their body, Parkinson s patients limbs tend to be either stiff or shake uncontrollably. Other non-motor symptoms like pain, sleep disturbances, irregular bowel movements, fainting spells, depression, anxiety, fatigue and memory problems also occur. There is no cure for the disease but medications and surgery can provide some relief.

Read more about Parkinson's disease.

Total Wellness is now just a click away.

Follow us on