A group of researchers from Germany and the US has found that both ageing and depression are associated with changes in a single gene. It can be regulated by the addition or removal of methyl (CH3) groups from an area of the gene called FKBP5. The researchers found that ageing can decrease the methylation process causing the FKBP5 gene to be over-expressed. (Read: 5 facts you didn t know about depression) They also found that when someone is depressed the demethylation process is accelerated even further. 'We found that both ageing and depression seem to lead to changes in how