Researchers have found a protein that can open new doors of treatment for IBD

Here's a breakthrough in health. Scientists have found a protein that can lead to new treatment and diagnosis for inflammatory bowel disorders (IBD)

Sreemoyee Chatterjee | Updated: September 25, 2018 7:55 pm

Now a new method of treatment for IBD © Shutterstock

Now, conditions like ulcerative colitis and Crohn’s disease can be better treated and diagnosed, thanks to a group of scientists that has pointed out a mechanism regulating gut inflammation in inflammatory bowel disorders (IBD). Role of a protein, RNF5, that is found in abundance in cells lining the gut, has been identified by the researchers at Sanford Burnham Prebys (SBP) Medical Discovery Institute in La Jolla, CA and Technion-Israel Institute of Technology in Haifa.

The researchers found that this protein controls the activity of another protein, S100A8, considered to be an active promoter of inflammation. According to a recent media report, the scientists manipulated the RNF5 gene in mice and found that this protein keeps S100A8 stable in cells of the gut lining. It was also found that absence of RNF5 releases the pro-inflammatory power of S100A8. This study appeared in the journal Cell Reports.

Experts say that inflammatory bowel disease (IBD) is the general term for an amalgamation of disorders that persistently inflame the gastrointestinal tract or gut. Crohn’s disease that has the ability to inflame any part of the gut between the mouth and the anus and ulcerative colitis that mostly affects the colon are two main kinds of inflammatory bowel disorders.

Published: September 25, 2018 7:55 pm | Updated:September 25, 2018 7:55 pm

Disclaimer: TheHealthSite.com does not guarantee any specific results as a result of the procedures mentioned here and the results may vary from person to person. The topics in these pages including text, graphics, videos and other material contained on this website are for informational purposes only and not to be substituted for professional medical advice.

5 things you must know before going under the knife for breast implants

World Pharmacist Day 2018: 5 right-ways of using over-the-counter or OTC medicines

About The health Site

TheHealthSite.com is India's largest health site with more than 40 lakh unique visitors per month. We focus on fitness, beauty, health, pregnancy and more.

Most popular health and wellness website in India in 2012 at the Website of the year awards.

health@corp.india.com

+91 – 22 – 6697 1234

91 – 22 – 2490 0302.

ZEE ENTERTAINMENT ENTERPRISES LTD, 18th floor, A-Wing, Marathon Futurex, N. M. Joshi Marg, Lower Parel, Mumbai, Maharashtra 400013.

We respect your privacy

5 things you must know before going under the knife for breast implants

World Pharmacist Day 2018: 5 right-ways of using over-the-counter or OTC medicines

About The health Site

Useful Links