Heart is known as the pump to the body which works in co-ordination with valves divided in between the left and the right ventricle. Researchers have discovered a new mechanism involved in a common congenital disease of the aortic valve located in the left ventricle. The findings of the study were published in the prestigious journal -- Nature Genetics. Valve disease affects two per cent of the population which is a significant proportion. Despite this high incidence and many signs that point to the role played by genetics in aortic diseases only a few genes have been identified to date.