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Researchers discover new fatty acids that can treat diabetes

With changing lifestyle patterns, the incidence of lifestyle diseases is also on the rise. Diabetes is one of major lifestyle diseases and according to the WHO statistics of 2012, every 10 person is diabetic. With such high incidence rates, researchers all across the world are trying to develop new treatment and preventive techniques to curb diabetes. A new study has recently discovered 'fats' that play an important role in fighting type 2 diabetes efficiently. (Read: Beverages with added sugar increasing the rate of diabetes)

These fats are a new class of potentially therapeutic lipids, called fatty-acid esters of hydroxy fatty acids (FAHFAs). They are usually found in people with insulin resistance. The study was conducted on diabetic mice. The FAHFAs when administered to these mice improved their glucose metabolism and insulin secretion. This finding paved new roads to develop novel therapeutic methods for the treatment of the disease.

Researchers at the Beth Israel Medical Deaconess Center found that they could create obese mice that were unusually sensitive to insulin and suspected that the lipids found in them were behind it. The research on these newly discovered fats could lead to a diabetes therapy.The researchers used mass spectrometry technique, to identify a total of 16 different types of FAHFAs in the mice. Then, these lipids were fed to insulin- resistant mice and it was observed that there had been an improvement in inflammation, insulin sensitivity and glucose uptake. (Read:5 types of heart disease common in type 2 diabetics)

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The researchers also measured FAHFA levels in the blood samples from human subjects, and found lower levels of these compounds in those with insulin resistance. Saghatelian said that they would be able to come up with better therapies to treat the disease with fewer side effects and that would be effective to a large number of people. (Read:Tea prevents type-2 diabetes )

The research would be described recently at the 249th National Meeting and Exposition of the American Chemical Society (ACS).

With inputs from ANI

Image source: Getty Images


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