Researchers at Duke University say that heavily dependent male smokers who do not repond to nicotine replacement might need to combine cessation methods in order to quit. 'The findings offer a potential practical treatment approach that can identify smokers who don't respond to a single conventional treatment but may benefit enormously from a combination of treatments' said Jed Rose Ph.D. director of the Duke Center for Smoking Cessation and the study's lead author. (Read: Are tobacco-less e-cigarettes less harmful?) The study involved 349 adult participants all of whom smoked at least 10 cigarettes per day and researchers determined their level
