Researchers have identified an enzyme that appears to drive the conversion of normal colon tissue into cancer by attaching sugar molecules or glycans to certain proteins in the cell. The research published in the Journal of Biological Chemistry showed that the enzyme was absent in healthy colon tissue but abundant in colon cancer cells. Our data suggest (that) this specific enzyme seems to affect a subset of proteins that could be involved in cell-cell adhesion said Hans Wandall from University of Copenhagen in Denmark. In other words the glycan modifications changed the patterns in which cells stuck together leading the
