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Home / Health News / Motor neuron disease symptoms may ease after taking this cannabis-based drug, finds study

Motor neuron disease symptoms may ease after taking this cannabis-based drug, finds study

A cannabis-based drug may help ease muscle movement for people suffering from motor neuron disease, the results of a clinical trial have shown.

By: Agencies   | | Published: December 15, 2018 11:40 am
Tags: Cannabis  Motor Neurone Disease  Neuron  
Motor neuron disease
Improved symptom control and quality of life are important for motor neuron disease patients. © Shutterstock

A cannabis-based drug may help ease muscle movement for people suffering from motor neuron disease, the results of a clinical trial have shown. Also Read - Cannabis therapy may reduce blood pressure in older adults

The study, published in The Lancet Neurology journal, showed that chemical compounds — delta-9 tetrahydrocannabinol THC and cannabidiol (THC-CBD) — derived from the cannabis sativa plant given as an add-on treatment may help ease symptoms of spasticity (tight or stiff muscles). Also Read - Using cannabis as painkiller can lead to withdrawal symptoms. Try these herbs instead



Spasticity is a rapidly progressive, fatal neurodegenerative disorder affecting the nerve cells that control muscle movement. It is a major cause of disability and reduced quality of life in people with motor neuron disease. Also Read - Marijuana and mental health: Don’t roll up a cannabis to destress!

Adults with motor neuron disease who took a combination of anti-spasticity drugs and cannabidiol experienced less spasticity and pain at six weeks follow-up compared with those given placeboes.

“There is no cure for motor neuron disease so improved symptom control and quality of life are important for patients,” said lead researcher Nilo Riva from the San Raffaele Scientific Institute in Italy.

“Our trial showed a beneficial effect of THC-CBD spray in people on treatment-resistant spasticity and pain,” Riva added.

However, there is a need to confirm the efficacy and safety of THC-CBD spray in larger, longer-term phase 3 trials, Riva said.

For the trial, the team included 60 adults (aged 18-80 years).

Spasticity and pain were significantly improved in the THC-CBD spray group compared with placebo.

Overall, THC-CBD spray was well tolerated and adverse events were mild to moderate, the researchers said.

Source: IANS

Published : December 15, 2018 11:40 am
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