A new study has discovered that inhibiting a previously known protein could reduce tumor burdens and enhance the effectiveness of immunotherapy treatments. Cancer immunotherapy is the use of the immune system to treat cancer. Immunotherapies can be categorized as active passive or hybrid. Researchers at the Bloomberg~Kimmel Institute for Cancer Immunotherapy investigated the role of the Yes-associated protein or YAP in T-cells in the cancer setting. Scientists used mice genetically engineered to lack YAP in several T-cell populations including regulatory T-cells known as Tregs. This was the first time the relationship between YAP and Tregs has been explored. Tregs are
