Agencies
... Read More
By clicking “Accept All Cookies”, you agree to the storing of cookies on your device to enhance site navigation, analyze site usage, and assist in our marketing efforts. Cookie Policy.
Written By: Agencies | Published : June 11, 2015 3:09 PM IST
Not getting enough sleep even for one night promotes biological aging among older adults, a new study suggests. These findings causally link sleep deprivation to the etiology of biological aging. The results also support the hypothesis that sleep deprivation may be associated with elevated disease risk because it promotes molecular processes involved in biological aging.
Our data support the hypothesis that one night of not getting enough sleep in older adults activates important biological pathways that promote biological aging, said lead author Judith Carroll, assistant professor of psychiatry and biobehavioral science at the University of California, Los Angeles. Read: Lack of sleep may damage your cells
The study group comprised 29 community-dwelling older adults in the age group of 61-86 years with 48 percent being male. They underwent an experimental partial sleep deprivation protocol over four nights, including adaptation, an uninterrupted night of sleep, partial sleep deprivation and another uninterrupted night of sleep (recovery). Blood samples were obtained each morning to assess PBMC gene expression using Illumina HT-12 arrays.
Results showed that one night of partial sleep deprivation activates gene expression patterns in peripheral blood mononuclear cells (PBMCs) consistent with increasing accumulation of damage that initiates cell cycle arrest and increases susceptibility to senescence.
The research was published online in the journal Sleep.
You may like to read:
Source: IANS
Image Source: Getty Images
For more articles on diseases & conditions, visit our diseases & conditions section. For daily free health tips, sign up for our newsletter.
