Switch to हिंदी

Health, Fitness, Beauty & Diet | Pregnancy & Parenting | Diseases & Home Remedies | TheHealthSite.com

Health, Fitness, Beauty & Diet | Pregnancy & Parenting | Diseases & Home Remedies | TheHealthSite.com

हिंदी
  • Health A-Z
  • Diabetes
  • Diseases
    • Type 1 Diabetes
    • Type 2 Diabetes
    • Cancer
    • Heart Attack
    • Pneumonia
    • Diseases A-Z
  • Diet & Fitness
    • Weight Management
    • Exercise & Body Building
    • Diet & Recipes
    • Yoga
  • Coronavirus
  • News
  • Pregnancy
    • Conceiving
    • Infertility
    • Labour & Delivery
    • Pregnancy week-by-week
    • Breastfeeding
    • Baby Names
  • Beauty
    • Skin
    • Hair
    • Grooming
  • Photos
  • Videos
Home / Health News / India’s first mRNA Covid-19 vaccine candidate gets nod to start clinical trials

India’s first mRNA Covid-19 vaccine candidate gets nod to start clinical trials

Meanwhile, two vaccine candidates -- Covishield and Covaxin - are in the third stage of clinical trials.

By: Satata Karmakar   | | Published: December 10, 2020 11:07 am
Tags: Coronavirus  Coronavirus Vaccine  coronavirus vaccine in India  COVID-19  
India's first mRNA vaccine receives approval for clinical trials
India's first mRNA vaccine receives approval for clinical trials

Drugs Controller General of India (DCGI) has given conditional approval for Phase 1 and 2 clinical trials of India’s first mRNA Covid-19 vaccine candidate — HGCO19 — that is being developed by Gennova Biopharmaceuticals. Also Read - Coronavirus vaccine: This nasal spray can block the virus for upto 2 days

Gennova Biopharmaceuticals, a Pune-based firm, is developing the vaccine candidate in collaboration with HDT Biotech Corporation, USA. It is India’s first messenger RNA (mRNA), Covid vaccine candidate. Globally, US-based pharma giant Pfizer Inc has developed its mRNA vaccine. Also Read - To vaccinate or not? Medical expert clears the air around Covid-19 vaccines



THE BACKGROUND OF THE VACCINE

The permission was granted after the Subject Expert Committee (SEC) for vaccines recommended for grant of permission in a review meeting on Wednesday. Also Read - Recovered from Covid-19? Your immune system may fight coronavirus variants

In a document, the DCGI had stated that, after a detailed deliberation, the committee recommended for grant of permission to conduct Phase 1/2 clinical trial subject to the condition that the interim results of Phase 1 study shall be submitted to the committee before proceeding to the next phase.

The Department of Biotechnology had earlier said it has provided seed funding for the development of Gennova’s novel self-amplifying mRNA-based vaccine candidate for Covid-19.

HOW THE mRNA WAS DEVELOPED

Gennova has developed its mRNA vaccine candidate (HGCO19) in collaboration with HDT Biotech Corporation, US. The firm earlier said that the vaccine demonstrated safety, immunogenicity, neutralisation antibody activity in the rodent and non-human primate models.

In an earlier statement, the DBT has stated that “DBT-BIRAC has facilitated the establishment of the first-of-its-kind mRNA-based vaccine manufacturing platform in India. DBT has provided seed funding for the development of Gennova’s novel self-amplifying mRNA-based vaccine candidate for COVID-19.”

VACCINES IN INDIA ARE UNDER TRIALS

The Union Health Ministry had on Tuesday said that as many as eight vaccine candidates for Covid-19 are under different stages of clinical trials and could be ready for authorisation in the near future.

The eight vaccines include Astrazeneca and Oxford University developed and Serum Institute of India manufactured Covishield, Covaxin by Bharat Biotech Ltd, ZyCoV-D by Zydus Cadila, Russian vaccine candidate Sputnik-V, NVX-CoV2373 by SII, HGCO19 by Geneva, and two unlabeled vaccines — the Recombinant Protein Antigen based vaccine by Biological E Ltd and Inactivated rabies vector platform by Bharat Biotech.

While the former five vaccine candidates are in either phase 2 or entered in phase 3 clinical trials, the latter three are still in pre-clinical trial phases.

COVISHIELD AND COVAXIN ARE IN THE THIRD STAGE OF TRIAL

Meanwhile, two vaccine candidates — Covishield and Covaxin – are in the third stage of clinical trials. They have applied for emergency use authorisation to the Drug Controller General of India (DCGI). Their application is pending approval after the SEC found inadequate safety and efficacy data of the vaccines in its Wednesday review meeting.

The SEC has recommended furnishing further safety and efficacy data to both the firms to receive the emergency use authorisation (EUA) of their Covid vaccines.

(With inputs from IANS)

Published : December 10, 2020 11:07 am
Read Disclaimer

No alcohol for 2 months after coronavirus vaccine shot, experts tell why

No alcohol for 2 months after coronavirus vaccine shot, experts tell why

Metformin, commonly used diabetes drug, lowers risk of death in COVID-19 positive women

Metformin, commonly used diabetes drug, lowers risk of death in COVID-19 positive women

Please Wait. Article Loading ....

Coronavirus Updates

Coronavirus Updates

Stay Informed, Be Safe

  • Coronavirus vaccine: This nasal spray can block the virus for upto 2 days
  • To vaccinate or not? Medical expert clears the air around Covid-19 vaccines
  • Recovered from Covid-19? Your immune system may fight coronavirus variants
  • Covid-19 variant detected in UK may be ‘more deadly than the older virus strain’
  • UK COVID Strain May Be More Infectious But There Is No Need To Panic: Experts

Health Calculators

BMI Calculator
bmi Calculator
Ideal Body Weight
ideal body weight
Daily Calorie Intake
Daily calorie intake
Calories Burned
calories burned

Related Stories

To vaccinate or not? Medical expert clears the air around Covid-19 vaccines

To vaccinate or not? Medical expert clears the air around Covid-19 vaccines

'Game changer against Covid-19': Expert panel recommends phase 1 trial of Bharat Biotech's nasal vaccine

'Game changer against Covid-19': Expert panel recommends phase 1 trial of Bharat Biotech's nasal vaccine

‘Don’t take Covid-19 vaccine shot if...': Covaxin company warns people amid concerns

‘Don’t take Covid-19 vaccine shot if...': Covaxin company warns people amid concerns

Covid-19 vaccine alert: Covishield not advised to those allergic to any of its ingredients

Covid-19 vaccine alert: Covishield not advised to those allergic to any of its ingredients

COVID-19 vaccine side effects: Loss of sensation in arms and more reported by Pune health workers

COVID-19 vaccine side effects: Loss of sensation in arms and more reported by Pune health workers

Health News in Hindi

Weight Loss Diet: वेट लॉस के लिए एक्सपर्ट्स मानते हैं लो-फैट डायट को बेस्ट, जानें इस डायट के अन्य फायदे

बर्मिंघम यूनिवर्सिटी के शोधकर्ता बना रहे हैं एक ऐसा ‘नेजल स्प्रे’ जो 2 दिनों तक कोरोनावायरस को शरीर में जाने से रोकेगा

लालू प्रसाद यादव की तबीयत में सुधार नहीं, इस गंभीर संक्रमण से हैं ग्रस्त, दिल्ली के एम्स में चल रहा है इलाज

Covid-19 Symptoms: सूंघने की क्षमता कम होना है कोविड-19 का सबसे बड़ा लक्षण, नयी रिसर्च का दावा

Hand Sanitizer: सावधान! क्या आपका बच्चा भी यूज़ करता है हैंड सैनिटाइज़र? जा सकती है बच्चों की आंख की रोशनी, जानें कैसे

Read All

Recent Posts

  • Thyroid: Do you constantly feel exhausted? It could be a sign of Hypothyroidism
  • Coronavirus vaccine: This nasal spray can block the virus for upto 2 days
  • To vaccinate or not? Medical expert clears the air around Covid-19 vaccines
  • Egg freezing on rise in India: Is it the best choice to make? Know the pros and cons
  • Recovered from Covid-19? Your immune system may fight coronavirus variants

About The health Site

TheHealthSite.com is India's largest health site with more than 40 lakh unique visitors per month. We focus on fitness, beauty, health, pregnancy and more.

Most popular health and wellness website in India in 2012 at the Website of the year awards.

health@corp.india.com
+91 – 22 – 6697 1234
Landline Phone number 91 – 22 – 2490 0302.

ZEE ENTERTAINMENT ENTERPRISES LTD, 18th floor, A-Wing, Marathon Futurex, N. M. Joshi Marg, Lower Parel, Mumbai, Maharashtra 400013.

Useful Links

  • Weight Loss
  • Keto Diet Tips
  • Skin Care Tips
  • Intermittent Fasting
  • Apple Cider Vinegar
  • Ashwagandha
  • Cancer
  • Pneumonia
  • Diarrhoea
  • Dengue
  • Typhoid
  • Tuberculosis
  • Chickenpox
  • Chikungunya
  • Depression
  • Hepatitis
  • Diabetes
  • Type 2 diabetes
  • Arthritis
  • Swine Flu
  • Baby Names
  • Cough and cold
  • Heart Attack
  • Breast Cancer
  • Ebola Virus
  • Dengue
  • Malaria
  • International Yoga Day
  • Hypotension
  • Heart Failure
  • Asthma
  • Brain Tumour
  • Celebrity Fitness
  • Goitre
  • HIV/AIDS

We respect your privacy

  • Disclaimer
  • Privacy Policy
  • Contact Us
  • Author Profiles

Copyright © 2021 Zee Entertainment Enterprises Limited. All rights reserved.