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Home / Health News / Indian doctors devise score to assess patients’ bleeding risk

Indian doctors devise score to assess patients’ bleeding risk

A score has been derived by doctors here to assess the bleeding risk in Indian patients who are on drugs that prevent clotting of blood.

By: Agencies   | | Published: October 22, 2013 3:28 pm
Tags: Bleeding  Blood clotting  In the news  

bloodA score has been derived by doctors here to assess the bleeding risk in Indian patients who are on drugs that prevent clotting of blood. Also Read - Shortness of breath could be a sign of blood clots in your body

Also Read - Why some COVID-19 patients should add these natural blood thinners to their meals



The research by geneticists at the Sir Ganga Ram Hospital here focused on deriving and validating a Genetic Bleeding Risk (GBR) score based on genetic and non-genetic factors associated with bleeding in patients on long-term anti-coagulation (blood clotting) therapy, a release said on Monday. Also Read - Ganesh Chaturthi 2020: 4 reasons an eco-friendly Ganesha is good for you

There are already a few bleeding risk prediction scores available in the world, but most are derived from the white population and more importantly, none have evaluated the predictive significance of genetic risk factors so far, it said.

A substance that prevents clotting of blood, anti-coagulants are being used all over the world since early 1940s for treatment and prevention of thrombosis – clot formation in a blood vessel that obstructs flow and affects various body parts and organs like legs, heart, kidneys, brain and lungs etc. (Read: Low-dose aspirin effective in preventing blood clots)

Despite its common usage, oral anti-coagulant (OAC) therapy is associated with significant bleeding complications.

The study was conducted on 310 patients from departments of vascular surgery, cardiac surgery and neurology from August 2009 to August 2012 at Sir Ganga Ram Hospital here. It took approval from the hospital’s ethics board committee and was in accordance with the ethical standards of World Medical Association.

‘The report shows that the number of bleeding episodes can be effectively reduced, thus sparing the patients from adverse outcomes and reducing hospital admissions,’ said Risha Nahar, scientist at the hospital’s Centre of Medical Genetics.

‘The present study is the first to devise and validate a genetic scoring scheme for predicting bleeding among first time users of oral anti-coagulants,’ he added.

Both genetic and non-genetic factors (drug-drug interactions, additional medical conditions, age, history of bleeding) are known to contribute towards bleeding or haemorrhage in patients on anti-coagulant therapy. (Read: Apples and oranges could keep blood clots, heart attacks and strokes away!)

Source: IANS

Published : October 22, 2013 3:28 pm
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