Hypertensive patients can now receive intensive treatments faster

The SPRINT trial included 9,361 non-diabetic hypertensive adults at an elevated risk of a cardiovascular event.

By: ANI | | Published: July 4, 2018 9:28 am

In a recent study, researchers have devised a machine learning algorithm which combines three variables routinely collected during clinic visits and demonstrates how the emerging field of bioinformatics could transform patient care.

“I think our algorithm can help us identify high-risk patients who will most likely benefit from intensive blood pressure reduction. Long-term intensive HBP drug therapy can reduce the risk of heart failure and death, but it carries an increased risk of side effects,” said another researcher, Wanpen Vongpatanasin. Read: Hypertension: 6 foods you must include in diet everyday

The researchers’ machine learning method determined three simple criteria to identify adults with high blood pressure who are at the highest risk for early major adverse cardiovascular events — such as cardiovascular death, heart attack, or stroke.

Those criteria are: an age of 74 or older, a Urine Albumin-to-Creatinine Ratio (UACR) of 34 or higher, and a history of a clinical cardiovascular disease, such as heart disease, stroke, or heart failure. Patients who met one or more of the three criteria were predicted to be among a high-risk group who had a greater benefit from intensive blood pressure-lowering treatment.

In contrast, the team found that patients younger than age 74 who had a UACR less than 34 and no history of cardiovascular disease may do equally as well with less intensive treatment. Read: World Hypertension Day 2017 – Treatment of high blood pressure with antibiotics

“We feel that our findings have major clinical implications since, in addition to its predictive effects, the model generated here is simple and easy to implement in clinical practice without additional lab tests or computational tools,” said Xie.

“We hope that clinicians can someday use this algorithm to identify which patients should receive standard versus intensive treatment, and we hope to design a prospective clinical trial to further validate this algorithm,” he added.

Source: ANI

Image Source: Shutterstock

Published : July 4, 2018 9:28 am

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