A new study has paved the way for the potential treatments of intellectual disability and other neurodevelopmental disorders. Your brain needs just the right balance between excitatory on signals and inhibitory calm down signals. Now scientists from the Florida campus of The Scripps Research Institute (TSRI) have shown that a protein helps balance nerve cell communication. This paper adds a new dimension to our understanding of the molecular mechanisms that impact intellectual disability said researcher Brock Grill. Our study is the first to identify a defect in neuron communication caused by altering the activity of a gene called HUWE1 which