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Home / Health News / Experimental gene therapy improves sight in patients with rare sight disorder called choroideremia

Experimental gene therapy improves sight in patients with rare sight disorder called choroideremia

Doctors helped two men suffering from progressive blindness to help regain some of their vision with the help of an experimental gene therapy.

By: Admin   | | Published: January 16, 2014 5:24 pm
Tags: Gene therapy  In the news  

geneDoctors helped two men suffering from progressive blindness to help regain some of their vision with the help of an experimental gene therapy. Also Read - Ganesh Chaturthi 2020: 4 reasons an eco-friendly Ganesha is good for you

After undergoing treatment to correct a faulty gene, the men were able to read two to four more lines on an optician’s sight chart, which was a significant improvement since the doctors treated them. One man got treated more than two years ago, the Guardian reported. (Read: Can gene therapy restore our sense of smell?)
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Choroideremia is an X-linked disorder, which means that it is caused by a faulty gene, called CHM, on the X chromosome. 
A genetically modified virus is used in the experimental therapy to smuggle healthy copies of the CHM gene into light-sensitive cells in the retina, and supporting tissue called retinal pigment epithelium. (Read: Fix for the damaged heart – retrograde gene therapy)
Also Read - Bubble Boy Disease: This rare but fatal immune disorder has a cure in gene therapy now

Surgeons injected 10bn modified virus particles behind the retinas of the first six patients in the trial.

The injected viruses then infect the eye cells, which uses the new CHM gene to treat the genetic disorder. (Read: Gene therapy to help the brain repair damaged neurons)

The study has been published in the journal The Lancet. 

Source: ANI

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Published : January 16, 2014 5:24 pm
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