Indian-origin researchers have identified an enzyme that serves as a critical trigger for the damaging inflammation that ultimately leads to macular degeneration the leading cause of vision loss among the elderly. The finding published in the journal Nature Medicine may allow doctors to halt the inflammation early on potentially saving patients from blindness. Almost 200 million people in the world have macular degeneration. If macular degeneration were a country it would be the eighth most populated nation in the world. That's how large a problem this is said Jayakrishna Ambati from University of Virginia School of Medicine in the US.