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Home / Health News / Did you know mitochondria is passed to offspring only through mother? See how and why

Did you know mitochondria is passed to offspring only through mother? See how and why

A gene responsible for the elimination of paternal mitochondria in the offspring has revealed how and why mitochondria are only passed on through a mother's egg and not the father's sperm.

By: Agencies   | | Published: June 27, 2016 7:02 pm
Tags: Genes  Offspring  
genes

A gene responsible for the elimination of paternal mitochondria in the offspring has revealed how and why mitochondria are only passed on through a mother’s egg and not the father’s sperm. Mitochondria, present inside the cells of nearly all multicellular animals, plants and fungi, organelles, plays an important role in generating the energy that cells need to survive. The findings showed that a gene CPS-6 serves as a paternal mitochondrial factor that is critical for its degradation. Further, the enzyme that CPS-6 encodes first breaks down the interior membrane of the paternal mitochondria before moving to the space within the inner membrane to breakdown mitochondrial DNA. CPS-6 plays a key role in initiating the self-destruction of paternal sperm, which likely benefits the embryo. (Read: Lead exposure during pregnancy can affect the offspring) Also Read - Junk DNA' affects risk of inherited cancer: Study

Also Read - Cold-parenting associated with premature ageing in offspring



Delayed removal of paternal mitochondria causes increased embryonic lethality, demonstrating that paternal mitochondrial elimination is important for normal animal development, the researchers explained. Shortly after a sperm penetrates an egg during fertilisation, the sperm’s mitochondria are degraded while the egg’s mitochondria persist. The paternal mitochondria were found to partially self-destruct before the mitochondria were surrounded by autophagosomes, which target components within a cell and facilitate their degradation, said Qinghua Zhou from the American Association for the Advancement of Science, a US-based nonprofit organisation. For the study, the team analysed sperm mitochondria or paternal mitochondria in Caenorhabditis elegans — a type of roundworm — during early stages of development. (Read: Sex guarantees less chances of developing diseases in offspring over time) Also Read - All you need to know about these 9 genes behind eyebrow colours

Source: IANS

Photo source: Getty images (Image for representational purpose only)

Published : June 27, 2016 7:02 pm
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