Switch to हिंदी

Health, Fitness, Beauty & Diet | Pregnancy & Parenting | Diseases & Home Remedies | TheHealthSite.com

हिंदी
  • Health A-Z
  • Home Remedies
  • Diseases
    • Type 1 Diabetes
    • Type 2 Diabetes
    • Cancer
    • Heart Attack
    • Pneumonia
    • Diseases A-Z
  • Diet & Fitness
    • Weight Management
    • Exercise & Body Building
    • Diet & Recipes
    • Yoga
  • Coronavirus
  • News
  • Pregnancy
    • Conceiving
    • Infertility
    • Labour & Delivery
    • Pregnancy week-by-week
    • Breastfeeding
    • Baby Names
  • Beauty
    • Skin
    • Hair
    • Grooming
  • Photos
  • Videos
Home / Health News / Diabetes drug may increase your risk of heart failure

Diabetes drug may increase your risk of heart failure

Researchers have found that rosiglitazone, a drug used to treat type 2 diabetes, is associated with an increased risk of heart problems, especially heart failure.

By: IANS   | | Published: February 7, 2020 10:33 am
Tags: Diabetes drug  Heart diseases  
diabetes
Since 2007, studies have reported conflicting findings about whether rosiglitazone increases the risk of heart attacks. @Shutterstock

Rosiglitazone belongs to a class of drugs called thiazolidinediones. It helps control blood sugar levels in patients with type 2 diabetes, but it can also increase the risk of serious heart problems, said the study, published in the journal The BMJ. Also Read - This diabetes drug may be used as adjunct therapy for treating HIV

“Our study suggests that when evaluating drug safety and performing meta-analyses focused on safety, individual patient level data (IPD) might be necessary to accurately classify all adverse events,” said the study researchers “By including these data in research, patients, clinicians, and researchers would be able to make more informed decisions about the safety of interventions,” they added. Also Read - Benefits of Viagra: Consumption of this pill may reduce the risk of heart diseases in men



Since 2007, studies have reported conflicting findings about whether rosiglitazone increases the risk of heart attacks. But these studies didn’t have access to the raw data from clinical trials and mostly relied on summary level data (e.g. results reported in publications and clinical trial registries), which are not as reliable when estimating the true safety profile of drugs. Also Read - WATCH: Are women at higher risk of death by cardiac arrest than men?

Recent efforts by Pharmaceutical company GlaxoSmithKline (GSK) – the maker of rosiglitazone – to make IPD available to external investigators, prompted a team of researchers to re-analyse the data and clarify some of the uncertainties about rosiglitazone’s cardiovascular risk. They analysed the results of more than 130 trials involving over 48,000 adult patients that compared rosiglitazone with any control for at least 24 weeks. IPD were available for 33 trials, which included 21156 patients; the remaining trials only had summary level data available.

When the researchers analysed the IPD from trials made available by GSK, they found rosiglitazone was associated with a 33 per cent increased risk of a composite cardiovascular event (heart attack, heart failure, cardiovascular and non-cardiovascular related death) compared with controls.

This was estimated from the 274 events among 11,837 rosiglitazone patients and 219 events among 9,319 control patients. These findings highlight the potential for different results derived from different data sources, and demonstrate the need for greater clinical trial transparency and data sharing to accurately assess the safety of drugs, the researchers added.

Published : February 7, 2020 10:33 am
Read Disclaimer

Pregnant women with high BP at greater heart disease risk

Pregnant women with high BP at greater heart disease risk

Forget masks and gloves, wash your hand frequently to avoid coronavirus infection

Forget masks and gloves, wash your hand frequently to avoid coronavirus infection

Please Wait. Article Loading ....

Coronavirus Updates

Coronavirus Updates

Stay Informed, Be Safe

  • Do Health Insurance Companies Cover COVID-19? Everything You Need To Know
  • Nashik Horror: 22 COVID Patients Dead As Tanker Leak Disrupts Oxygen Supply
  • COVID-19 Live Updates: India sees 2,023 deaths in past 24 hours
  • COVID-19: Multivitamins, Omega-3 May Cut Coronavirus Infection Risk In Women
  • Second Coronavirus Wave: India Reports 2,95,041 New COVID-19 Cases, 2023 Deaths In 24hrs

Health Calculators

BMI Calculator
bmi Calculator
Ideal Body Weight
ideal body weight
Daily Calorie Intake
Daily calorie intake
Calories Burned
calories burned

Related Stories

Higher body fat in women linked to reduced risk of heart diseases

Higher body fat in women linked to reduced risk of heart diseases

This diabetes drug may be used as adjunct therapy for treating HIV

This diabetes drug may be used as adjunct therapy for treating HIV

Benefits of Viagra: Consumption of this pill may reduce the risk of heart diseases in men

Benefits of Viagra: Consumption of this pill may reduce the risk of heart diseases in men

Beta blockers will not make you depressed, but it can interfere with a good night’s sleep

Beta blockers will not make you depressed, but it can interfere with a good night’s sleep

Heart diseases in India: Remote monitoring can significantly reduce fatal outcomes of cardiac ailments

Heart diseases in India: Remote monitoring can significantly reduce fatal outcomes of cardiac ailments

Health News in Hindi

कमजोर इम्यूनिटी वाले यूं रखें कोरोनावायरस संक्रमण से खुद को बचाकर, पढ़ें एक्सपर्ट के ये सुझाव

दिल्ली में कोरोना मरीजों को चाहिए इतना ऑक्सीजन लेकिन सरकार के पास आधा भी नहीं, जानें दिल्ली को कितनी ऑक्सीजन की जरूरत

गोवा में सख्त पाबंदियां लगाने का ऐलान, 30 अप्रैल तक रात 10 बजे से सुबह 6 बजे तक रहेगा नाइट कर्फ्यू

ऑक्सीजन लेवल बढ़ाने के नाम पर भूलकर भी न सूंघें लौंग, कपूर और अजवाइन की पोटली, ऑक्सीजन की जगह शरीर में घुल जाएगा जहर

1 मई से 18 साल से ऊपर के हर व्‍यक्ति को लगाई जाएगी कोरोना वैक्‍सीन, मगर ये एक बात जो आप से छिपाई गई!

Read All

Recent Posts

  • India Ramps Up Remdesivir Production From 38 Lakh Vials Per Month to 74 Lakh Vials: Health Ministry
  • Things that can impact your child’s bone development
  • Do Health Insurance Companies Cover COVID-19? Everything You Need To Know
  • Covaxin Can Effectively Neutralise The Double Mutant Strain: ICMR
  • Nashik Horror: 22 COVID Patients Dead As Tanker Leak Disrupts Oxygen Supply

About The health Site

TheHealthSite.com is India's largest health site with more than 40 lakh unique visitors per month. We focus on fitness, beauty, health, pregnancy and more.

Most popular health and wellness website in India in 2012 at the Website of the year awards.

health@corp.india.com
+91 – 22 – 6697 1234
Landline Phone number 91 – 22 – 2490 0302.

ZEE ENTERTAINMENT ENTERPRISES LTD, 18th floor, A-Wing, Marathon Futurex, N. M. Joshi Marg, Lower Parel, Mumbai, Maharashtra 400013.

Useful Links

  • Weight Loss
  • Keto Diet Tips
  • Skin Care Tips
  • Intermittent Fasting
  • Apple Cider Vinegar
  • Ashwagandha
  • Cancer
  • Pneumonia
  • Diarrhoea
  • Dengue
  • Typhoid
  • Tuberculosis
  • Chickenpox
  • Chikungunya
  • Depression
  • Hepatitis
  • Diabetes
  • Type 2 diabetes
  • Arthritis
  • Swine Flu
  • Baby Names
  • Cough and cold
  • Heart Attack
  • Breast Cancer
  • Ebola Virus
  • Dengue
  • Malaria
  • International Yoga Day
  • Hypotension
  • Heart Failure
  • Asthma
  • Brain Tumour
  • Celebrity Fitness
  • Goitre
  • HIV/AIDS

We respect your privacy

  • Disclaimer
  • Privacy Policy
  • Contact Us
  • Author Profiles

Copyright © 2021 Zee Entertainment Enterprises Limited. All rights reserved.