Cell migration mechanism can cause breast cancer, later spreading to bones

A recent study published in the journal Scientific Reports, found that when a cancer cell gets very close to a bone cell, it exhibits low tensions and slow mobility.

By: ANI | | Updated: June 6, 2019 2:45 pm

Cell migration can generate breast cancer which later settles in the bones. ©Shutterstock

A recent study examined the mechanisms of cell migration which further states how breast cancer cells generate and later settle into the bones.

A Forster Resonance Energy Transfer-based tension, or FRET, the sensor was used to monitor the force dynamics during cell movement. The sensor, equipped with FRET molecules, acts like a spring to measure the tiny amount of force that is generated by the cancer cell through focal adhesion and that drives the cell to move. As the cancer cell moves, the spring expands; researchers measure the force by monitoring the change of FRET interactions.

Researchers monitored the mobility of the cancer cells and found that when a cancer cell gets very close to a bone cell, it exhibits low tensions and slow mobility. The researchers hope this finding might lead to clues for how to control — and eventually, stop — cell migration.”This gives us a more precise measurement of how fast the cell is moving and where the cell will go to,” Liu said.

He further went on to say, “The basic idea is to use imaging as a method to see some of the physical parameters in cancer biology. Instead of only being able to look at millions of cells at time, technology has enabled us to examine a single cell. When the system is going smaller and smaller, the physical parameters inside the biological system become more and more useful and more and more important.

Published : June 6, 2019 2:23 pm | Updated:June 6, 2019 2:45 pm

Read Disclaimer

More than 2 eggs daily can up your risk of cardiovascular diseases

Sports can help kids in fighting emotional distress

About The health Site

Useful Links