A recent analysis has found a dose-response relationship between higher cannabis use and increased risk for schizophrenia a condition associated with abnormal dopamine synthesis and release in the brain. In the study published in the journal of Addiction Biology researchers studied the effects of cannabis on brain neurochemistry and specifically about its impact on dopamine signalling. Regular use has a profound effect on cortical dopamine function in particular in relation to the stress response which is critical for young adults at risk for psychosis. These results highlight the need for further research on the impact of cannabis on brain neurochemistry
