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A cardiovascular disease is one of the common causes of death worldwide. According to the World Health Organization (WHO), about 19.8 million people died from CVDs in 2022, representing approximately 32% of all global deaths, where as 85% were due to heart attack and stroke.
Heart attacks usually occur due to interrupted blood flow to the brain. This incident happens when there is a build-up of fatty deposits on the inner walls of the blood vessels that supply the heart or brain. Apart from it, heart attacks have long been linked to poor diet, smoking and hypertension. Interestingly new study suggests that oral bacteria may also play a significant role in fatal heart attacks.
In a study published in the Journal of the American Heart Association (JAHA) on August 6, 2025, researchers from Finland reveal that mouth bacteria, mainly Viridans Streptococci, can trigger a chain reaction that impacts the arteries and subsequently causes a heart attack.
The findings were concluded by analysing coronary plaque from 121 individuals who lost their lives outside of hospitals and artery samples from 96 vascular surgery patients. The researchers detected bacterial DNA in nearly half the cases, with viridans streptococci being the most common bacteria found, appearing in 42% of coronary plaques and 43% of surgical samples.
Finland researchers conducted the analysis using bacterial real time quantitative polymerase chain reaction, immunohistochemistry, and genome wide expression analysis. It shows that a simple bacteria turn into a major health hazard as it settles in atherosclerotic plaques and forms biofilms, a bacterial communities that shield antibiotics from reaching and sometimes even immune cells (macrophages) can't detect.
When plaque ruptures, bacterial particles are released, triggering a significant immune response. As a result, this inflammation can destabilise arterial walls and cause sudden rupture, leading to heart attacks. According to laboratory tests, the Viridans Streptococci strain, TLR2 was the most activated bacterial-signalling pathway that contributes to arterial inflammation.
This breakthrough underscores the importance of oral hygiene in reducing the risk of cardiovascular disease. Follow these essential tips outlined by the Centere for Disease Control and Prevention (CDC) to prevent the formation of bacterial biofilms in arteries:
"Good oral health helps you enjoy life. It lets you: speak clearly; taste, chew, and swallow delicious and nutritious foods; and show your feelings through facial expressions such as smiling," the National Institute of Health (NIH) explains.
"If you protect your oral health with good oral hygiene practices (brushing and flossing), the odds are in your favour that you can keep your teeth for a lifetime."
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Ensure to brush your teeth for at least two minutes each time.
Viridans Streptococci (VS) are a group of bacteria that are harmless but can cause several systemic diseases, such as endocarditis, abscesses, and septicemia.
Gum disease is an infection of the gums caused by plaque buildup.
You should visit your dentist at least once in 6 months.