Post-menopausal women should think twice before going in for hormone replacement therapy (HRT) because it is tied to breast cancer globally reveals a study. The study by McMaster University researchers that found consistent evidence that use of HRT is linked to breast cancer globally comes at a time when more women are asking for this medication to control hot flashes and other symptoms of menopause. The rising trend is at odds with a US Women's Health Initiative (WHI) study of 2002 which found a higher incidence of breast cancer heart attack and stroke among women using HRT the