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Home / Health News / Better medicines for high blood pressure maybe on its way

Better medicines for high blood pressure maybe on its way

University of Southern Denmark researchers have found how a mutated protein can lead to holes in a protein sitting in a cell’s membrane. Such holes cause high blood pressure, and the discovery can n

By: Agencies   | | Published: January 29, 2014 4:54 pm
Tags: High Blood Pressure  In the news  

blood pressureUniversity of Southern Denmark researchers have found how a mutated protein can lead to holes in a protein sitting in a cell’s membrane. Such holes cause high blood pressure, and the discovery can now lead to new and better medication for high blood pressure. High blood pressure can be caused by many things – one of them being a specific mutated protein. Now the researchers at University of Southern Denmark have found out exactly what unfortunate events in the human organism are initiated by the mutated protein. Also Read - Commonly used blood pressure medications safe for COVID-19 patients

‘This knowledge can now lead to new and better medicines for high blood pressure’, lead author of a new scientific publication, PhD student Wojciech Kopec from the Center for Biomembrane Physics (MEMPHYS) at the University of Southern Denmark, said. (Read: Want to lower your blood pressure? Be happy!) Also Read - Rajinikanth being treated for severe hypertension: Check your blood pressure regularly



He explains that some years ago research colleagues from University of Aarhus found out that a particular mutated protein is associated with high blood pressure. But the exact mechanism at play could not be clarified until now. Wojciech Kopec and his colleagues, Himanshu Khandelia and Bastien Loubet from Memphys and Hanne Poulsen from University of Aarhus, have now revealed the mechanism at play: The mutated protein leads to the formation of holes in a protein sitting in a cell’s membrane, and so the cell can no longer control what is allowed into and out of the cell interior. The holes are made where the cell controls its content of salts. Also Read - Hypertension: Regulate blood pressure with these 5 yoga poses

A normal, healthy cell has full control of how much salt (sodium ions) must be removed from within the cell so that it can maintain a perfect salt balance in the organism, it is a part of. ‘But when there are holes, sodium ions can penetrate into the cell, so the salt levels go up. Too high salt levels are associated with many diseases, including high blood pressure’, Kopec said. This specific knowledge is particularly useful for the medical industry involved with developing new drugs. (Read: 10 ways hypertension or High BP affects your body)

Source: ANI

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Published : January 29, 2014 4:54 pm
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