We have been told many times that popping antibiotics for common infections is not ideal as they have a negative effect on the micro organisms in the stomach. The findings of a new study have further strengthened this fact, where it says that the impact of antibiotics on the gut of an animal is broader and more complex than previously thought. The study carried out at Oregon State University also says that long term use of antibiotics have far reaching effects. (Read:Is taking antibiotics too often bad for your health? ) Also Read - Antibiotic resistance looms large; New class of drugs may help fight the challenge Also Read - Are antibiotics safe for teenagers - What to expect?
Overuse of antibiotics can have unwanted effects on immune system, glucose metabolism, food absorption, obesity, stress and behaviour. The issues are rising in importance, since 40 percent of all adults and 70 percent of all children take one or more antibiotics every year, not to mention their use in billions of food animals. Although when used properly antibiotics can help treat life-threatening bacterial infections, more than 10 percent of people who receive the medications can suffer from adverse side effects. (Read: Decoded how microbes make antibiotics) Also Read - Foods to avoid if you're taking antibiotics
Researcher Andrey Morgun said that prior to this most people thought antibiotics only depleted microbiota and diminished several important immune functions that take place in the gut, which actually is only about one-third of the picture. Morgun added that they also kill intestinal epithelium and destruction of the intestinal epithelium is important because this is the site of nutrient absorption, part of our immune system and it has other biological functions that play a role in human health. The research also found that antibiotics and antibiotic-resistant microbes caused significant changes in mitochondrial function, which in turn can lead to more epithelial cell death. (Read: How do bacteria get resistant to antibiotics?)
Morgun concluded that when the host microbe communication system gets out of balance it can lead to a chain of seemingly unrelated problems.The work is published online in the journal Gut.
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Published : February 12, 2015 11:01 am