It turns out that the Alzheimer's disease could be already ‘at work’ in the brain while the actual symptoms appear years later. Indiana University investigators showed that the best-known genetic variant linked to Alzheimer's disease may be promoting deposits of plaque in the brain long before any symptoms of the disease can be measured on tests. The study focused on people with ‘significant memory concerns,’ defined as older adults who complained that they had mentally slipped in recent months or years, but when given standard cognition and memory tests they fell within normal ranges. People in this category have also