Acne? A vaccine for pimples may soon be on the anvil

Instead of invading pathogens, the new vaccine would be the first to target bacteria already in human skin. The researchers demonstrated that antibodies to a toxin secreted from bacteria in acne vulgaris can reduce inflammation in human acne lesions.

By: Agencies | | Updated: August 30, 2018 3:30 pm

An acne vaccination could circumvent potential adverse effects of topical or systemic retinoids and antibiotics © Shutterstock

Do you often suffer from acne? Take heart, a potential vaccine that targets the bacterial toxins may soon be on the anvil, say researchers. Instead of invading pathogens, the new vaccine would be the first to target bacteria already in human skin. The researchers demonstrated that antibodies to a toxin secreted from bacteria in acne vulgaris can reduce inflammation in human acne lesions.

“While addressing an unmet medical need and providing an appealing approach, acne immunotherapies that target P. acnes-derived factors have to be cautiously designed to avoid unwanted disturbance of the microbiome that guarantees skin homeostasis,” said Emmanuel Contassot, from the University of Zurich in Switzerland.

Future studies will address these factors and focus on engineering a non-toxic chemical or targeted vaccine formulation for its human application, the researchers said.

Source: IANS

Published : August 30, 2018 3:28 pm | Updated:August 30, 2018 3:30 pm

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