Switch to हिंदी

Health, Fitness, Beauty & Diet | Pregnancy & Parenting | Diseases & Home Remedies | TheHealthSite.com

Health, Fitness, Beauty & Diet | Pregnancy & Parenting | Diseases & Home Remedies | TheHealthSite.com

हिंदी
  • Health A-Z
  • Home Remedies
  • Diseases
    • Type 1 Diabetes
    • Type 2 Diabetes
    • Cancer
    • Heart Attack
    • Pneumonia
    • Diseases A-Z
  • Diet & Fitness
    • Weight Management
    • Exercise & Body Building
    • Diet & Recipes
    • Yoga
  • Coronavirus
  • News
  • Pregnancy
    • Conceiving
    • Infertility
    • Labour & Delivery
    • Pregnancy week-by-week
    • Breastfeeding
    • Baby Names
  • Beauty
    • Skin
    • Hair
    • Grooming
  • Photos
  • Videos
BLA21 cibil.com ageas federal zee hindustan
Home / Health News / A new stem cell therapy promises to heal injured heart

A new stem cell therapy promises to heal injured heart

According to a new study, a novel stem cell therapy may help your heart recover from an attack. Read on to know more.

By: ANI   | | Published: November 30, 2019 11:06 am
Tags: Stem cell research  Stem cell therapy  
stem cell therapy
The innate immune response acutely altered cellular activity around the injured area of the heart so that it healed with a more optimized scar and improved contractile properties. ©Shutterstock

This study published in the journal Nature reported that injecting living or even dead heart stem cells into the injured hearts of mice triggers an acute inflammatory process, which in turn generates a wound healing-like response to enhance the mechanical properties of the injured area. Also Read - Tendon stem cells can revolutionise injury recovery: Study

Mediated by macrophage cells of the immune system, the secondary healing process provided a modest benefit to heart function after a heart attack, according to the principal investigator Jeffery Molkentin, PhD, director of Molecular Cardiovascular Microbiology a Cincinnati Children’s Hospital Medical Center and a professor of the Howard Hughes Medical Institute (HHMI). Also Read - Green signal to man for neuro muscular treatment



“The innate immune response acutely altered cellular activity around the injured area of the heart so that it healed with a more optimized scar and improved contractile properties,” Molkentin said. Also Read - New therapy may help treat Parkinson's disease

The findings build on a 2014 study published by the same research team. As in that earlier study, the current paper shows that injecting c-kit positive heart stem cells into damaged hearts as a strategy to regenerate cardiomyocytes doesn’t work.

The findings prompted Molkentin and his colleagues to conclude that there is a need to “re-evaluate the current planned cell therapy based clinical trials to ask how this therapy might really work.”

Researchers worked with two types of heart stem cells currently used in the clinical trials — bone marrow mononuclear cells and cardiac progenitor cells.

As they went through the process of testing and re-verifying their data under different conditions, they were surprised to discover that in addition to the two types of stem cells, injecting dead cells or even an inert chemical called zymosan also provided benefit to the heart by optimizing the healing process. Zymosan is a substance designed to induce an innate immune response.

They reported that stem cells or zymosan therapies tested in this study altered immune cell responses that significantly decreased the formation of extracellular matrix connective tissue in the injury areas, while also improving the mechanical properties of the scar itself.

Researchers also found that stem cells and other therapeutic substances like zymosan have to be injected directly into the hearts surrounding the area of infarction injury.

“Most of the current trials were also incorrectly designed because they infuse cells into the vasculature. Our results show that the injected material has to go directly into the heart tissue flanking the infarct region. This is where the healing is occurring and where the macrophages can work their magic,” Molkentin explained.

Published : November 30, 2019 11:06 am
Read Disclaimer

Prostate cancer can rely on immunotherapy for treatment: Study

Prostate cancer can rely on immunotherapy for treatment: Study

Increased screen time may impact child development: Study

Increased screen time may impact child development: Study

Please Wait. Article Loading ....

Coronavirus Updates

Coronavirus Updates

Stay Informed, Be Safe

  • 'Coronil is evidence based medicine': Ramdev's Patanjali issues fact check response to IMA
  • COVID-19 vaccine for above 45: How to register and who is eligible? Everything answered
  • Hospitalised COVID-19 patients with sodium imbalance at high risk of respiratory failure, sudden death
  • Indian company develops triple-combination pills for migraine, gets FDA approval
  • Is it safe to travel if you have got the COVID-19 vaccine? Here's what experts say

Health Calculators

BMI Calculator
bmi Calculator
Ideal Body Weight
ideal body weight
Daily Calorie Intake
Daily calorie intake
Calories Burned
calories burned

Related Stories

Stem Cells and Cancer - India 2018 symposium brings together cancer experts to spread awareness about stem cell research

Stem Cells and Cancer - India 2018 symposium brings together cancer experts to spread awareness about stem cell research

India can excel in stem cell therapy with new policies

India can excel in stem cell therapy with new policies

How does my baby's umbilical cord play a role in stem cell treatment?

How does my baby's umbilical cord play a role in stem cell treatment?

Stem cell treatment -- a boon for burn victims

Stem cell treatment -- a boon for burn victims

Stem cells grown on fluffier mediums function better!

Stem cells grown on fluffier mediums function better!

Health News in Hindi

Pregnancy Symptoms: प्रेग्नेंसी के पहले महीने में नजर आने वाले संकेत और लक्षण

सेब के साथ इन चीजों का सेवन सेहत के लिए ठीक नहीं, जानें क्या हो सकते हैं नुकसान

Children And Mental Health: ये 5 संकेत बताते हैं कि आपका बच्चा मानसिक विकार से है ग्रसित

Stevia Side Effects: नेचुरल स्वीटनर स्टीविया हर्ब के फायदे ही नहीं इसके 5 नुकसान भी जानें

Vaccination for Children: बच्चे को वैक्सीन लगवाना भूल जाएं तो घबराएं नहीं, ‘कैच-अप वैक्सीनेशन’ की लें मदद

Read All

Recent Posts

  • New method can diagnose COVID-19 in less than 55 minutes: Here’s how
  • Healthy dessert recipes to beat sugar cravings when trying to lose weight
  • Kim Kardashian owes her fitness to a plant-based diet; What you need to know
  • ‘Coronil is evidence based medicine’: Ramdev’s Patanjali issues fact check response to IMA
  • Engage your core: The best workouts to lose belly fat fast

About The health Site

TheHealthSite.com is India's largest health site with more than 40 lakh unique visitors per month. We focus on fitness, beauty, health, pregnancy and more.

Most popular health and wellness website in India in 2012 at the Website of the year awards.

health@corp.india.com
+91 – 22 – 6697 1234
Landline Phone number 91 – 22 – 2490 0302.

ZEE ENTERTAINMENT ENTERPRISES LTD, 18th floor, A-Wing, Marathon Futurex, N. M. Joshi Marg, Lower Parel, Mumbai, Maharashtra 400013.

Useful Links

  • Weight Loss
  • Keto Diet Tips
  • Skin Care Tips
  • Intermittent Fasting
  • Apple Cider Vinegar
  • Ashwagandha
  • Cancer
  • Pneumonia
  • Diarrhoea
  • Dengue
  • Typhoid
  • Tuberculosis
  • Chickenpox
  • Chikungunya
  • Depression
  • Hepatitis
  • Diabetes
  • Type 2 diabetes
  • Arthritis
  • Swine Flu
  • Baby Names
  • Cough and cold
  • Heart Attack
  • Breast Cancer
  • Ebola Virus
  • Dengue
  • Malaria
  • International Yoga Day
  • Hypotension
  • Heart Failure
  • Asthma
  • Brain Tumour
  • Celebrity Fitness
  • Goitre
  • HIV/AIDS

We respect your privacy

  • Disclaimer
  • Privacy Policy
  • Contact Us
  • Author Profiles

Copyright © 2021 Zee Entertainment Enterprises Limited. All rights reserved.