Dr Reddy`s Laboratories Ltd recalled 13,560 bottles of the high blood pressure drug metoprolol succinate in the United States after it failed a dissolution test, the U.S. Food and Drug Administration said. Metoprolol succinate extended release is a cheaper generic form of AstraZeneca Plc`s Toprol XL. Wockhardt Ltd also recalled 109,744 bottles of the same drug last month citing the same reason. The recall was voluntarily started by Dr Reddy`s on May 23, 2014, and posted on the FDA website on Thursday.
A Dr Reddy`s spokesman did not immediately respond to a request for comment on the recall. Dissolution tests are commonly conducted to check the time taken for the active ingredient in a drug to release into the body, and help predict how the drug performs inside the body. The Dr Reddy`s recall, like the one by Wockhardt, was classified by the FDA as Class II, which means use of or exposure to the recalled products may cause temporary or medically reversible adverse health consequences. (Read: If you have heart disease, read this before you visit the dentist)
This is the latest in a string of drug recalls and manufacturing quality-related issues involving Indian companies that have hurt the reputation of the industry as a supplier of cheap generic drugs, and led to increased scrutiny from regulators. Dr Reddy`s recalled about 58,656 bottles of the heartburn drug lansoprazole in the United States in March due to a microbial contamination. (Read: 10 causes of chest pain you should know)
What is angina?
Angina, also called angina pectoris, is the medical term used to describe chest pain or a feeling of tightness, heaviness and discomfort in the chest as a result of inadequate blood oxygen supply to the heart muscle. The insufficient supply of oxygen is mainly caused by narrowing of arteries that carry blood to the heart (coronary arteries). It's the main symptom of coronary heart disease and is commonly mistaken as a symptom of indigestion. Angina often occurs when a person is under emotional or physical stress. Although pain is commonly felt in the chest, many a times pain in shoulders, arms, neck, throat, jaw or back is also experienced. There are different types of angina. The most common type of angina is stable angina which suggests the likelihood of getting a heart attack in near future. Unstable angina is severe than stable angina and requires emergency treatment. In this section, you'll find articles including the risk of heart attack in night shift workers, angioplasty and tips to keep your heart healthy. Read more about Angina causes, risk factors, symptoms, diagnosis and treatment.
With inputs from PTI
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