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Written By: Admin | Published : April 22, 2013 5:11 PM IST
A carcinoma that is localized and has not yet invaded into the surrounding tissue is termed carcinoma in situ. It is a pre-malignant condition that may, if left untreated, progress into a malignant cancer. The cells show signs of malignancy, but histologically there is no sign of invasion through the epithelial basement membrane. Carcinoma in situ is surgically removed to eliminate the risk of its progression into a life-threatening carcinoma. Some examples are ductal carcinoma in situ of the breast, Bowen s disease of the skin, etc.