Advertisement

What Role Does Nuclear Medicine Play In The Management Of Cancer?

A healthcare provider may recommend nuclear medicine procedure to diagnose or treat a health problem. It shows how the organs or tissues are functioning.

Written By Prerna Mittra
Updated : April 29, 2024 6:25 PM IST

Next-generation sequencing (NGS) allows rapid and cost-effective sequencing of targeted gene panels, facilitating the diagnosis of rare genetic disorders. Whole-genome sequencing (WGS) analyses an individual's entire DNA sequence, identifying genetic variations linked to rare diseases. Microarray tests simultaneously analyse thousands of genetic markers, diagnose rare diseases, and identify chromosomal abnormalities.

Cancer can affect any part of the body, and with advancements in medical science, it is possible to prevent it, or slow down its spread to other areas of the body by doing routine and timely tests and checkups, and going for preventive procedures. Nuclear medicine, it is understood, plays a crucial role in the management of cancer, offering 'innovative treatments' that target tumors with precision. According to the Centers for Disease Control and Prevention (CDC), nuclear medicine uses 'radioactive material' inside the body to see how organs or tissue are functioning (for diagnosis) or to target and destroy damaged or diseased organs or tissue (for treatment). What does it mean for oncology?

Precision Medicine Approach

"Nuclear medicine has shown promising results in various types of cancers, such as lymphoma and breast cancer. Additionally, nuclear imaging techniques like PET scans allow for accurate staging and monitoring of tumor progression, guiding treatment decisions for better outcomes," said Dr Gaurav Jaswal, head of the department of radiation oncologist, Onco Life Care Cancer Center, Chiplun.

Advertisement

The doctor added that another exciting development in nuclear medicine is 'theragnostic', which is a personalised approach that combines therapy and diagnostics using radiopharmaceuticals. By identifying specific molecular targets within tumors through imaging, clinicians can tailor treatment regimens for patients.

"This precision medicine approach not only improves therapeutic efficacy but also mitigates potential side effects associated with traditional treatments like chemotherapy or surgery. The growing intersection of nuclear medicine and oncology holds great potential for revolutionising cancer care by offering more targeted and effective therapies," said Dr Jaswal.

Advertisement

When Is Nuclear Medicine Procedure Used?

The CDC states that your healthcare provider may recommend a nuclear medicine procedure to diagnose or treat a health problem. It shows how the organs or tissues are functioning. For most diagnostic procedures, a tracer containing the radioactive material is injected, swallowed, or inhaled. The radiologist uses a radiation detector to see how much of the tracer is absorbed or how it reacts in the organ or tissue.

Use Of PET Scans In Oncology

The use of PET scans in oncology has revolutionised the way we diagnose and monitor cancer. By utilising radioactive tracers in PET scans, they can detect even the smallest traces of cancer cells in the body, allowing for early detection and more effective treatment planning, said Dr Ahalya Nair, nuclear medicine physician at Onco Life Cancer Center, Satara.

According to the doctor, these scans provide information on the tumors, helping doctors determine their 'aggressiveness and response' to treatment. "By tracking changes in metabolic activity over time, doctors can see how well a patient is responding to treatment and make necessary adjustments, if needed. This real-time monitoring can lead to personalised treatment plans that are tailored to each individual's unique cancer profile," said Dr Nair.

The doctors concluded by saying that nuclear medicine and PET scans deliver radiation directly to cancer cells while minimising damage to surrounding healthy tissues, offering new hope for patients with advanced or metastatic disease.