How can I get relief from Migraine? What is the treatment for Migraine? Resting in a darkened room without any noise often reduces the severity of symptoms. Put a cold compress over your forehead. Massage your scalp using a lot of pressure. Put pressure on your temples. Migraines can be treated with two approaches: Abortive and Preventive. Abortive: The goal of this therapy is to stop it once it starts. Abortive drugs include the triptans which specifically target serotonin. Nonprescription medicines that can help relieve migraine pain include aspirin acetaminophen aspirin and caffeine combination ibuprofen naproxen and ketoprofen. People with