Vitamin D May Reverse Ageing Age By Up to 3 Years: Here’s How Much Vitamin D You Need To Take Daily

Despite its ground-breaking findings, overdose of Vitamin D can cause hypercalcemia leading to nausea, kidney issues, or calcium deposits.

Vitamin D May Reverse Ageing Age By Up to 3 Years: Here’s How Much Vitamin D You Need To Take Daily

Written by N. Lothungbeni Humtsoe |Published : August 27, 2025 9:27 PM IST

Vitamin D Benefits: Although retinol may have the industry's stamp of approval for reverse ageing. Harvard-affiliated researchers have come forward with their groundbreaking study that a daily dose of Vitamin D can actually help preserve DNA and keep people biologically younger as much as three years.

The study, which is now published in the American Journal of Clinical Nutrition, revealed that researchers conducted the trial, called VITAL, which tracked over 1,000 adults for four years.

Scientists tested about 2,000 International Units (IU) daily of vitamin D3, which is about three times the usual daily dose but below the upper safe dose of 4,000 IU. The participants taking the vitamin D showed significantly less DNA damage and more gradual telomere shortening than those who received a placebo.

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Participants Receiving Vitamin D Showed Significantly Less DNA Damage

Dr. JoAnn Manson, principal investigator of VITAL and chief of the Division of Preventive Medicine at Brigham and Women's Hospital, told a leading media outlet, "Our findings that vitamin D supplementation preserved telomere length in the VITAL trial suggest a promising role for vitamin D in slowing a pathway for biological ageing and age-related chronic disease.

"But we believe that replication of these results in a separate randomized trial will be important before changing general guidelines for vitamin D intake. That's partly because what is considered an appropriate level of vitamin D remains, as she put it, "a controversial topic."

Manson added, "Blood levels for deficiency and recommended blood levels vary across organizations, labs and countries, which is one of the reasons for doubt about the test's usefulness. For example, the National Academy of Medicine suggests a level at or above 20 milliliters (mL), but some other organizations recommend 30 mL or even higher levels. There's no consensus or agreement on the optimal level to aim for."

How To Use Vitamin D Safely?

Despite the ground-breaking result, experts cautioned against overuse. Most adults are recommended to take 600 to 800 IU, while the most commonly recommended safe dose comes between 1000-2000 IU. Consuming more than 4,000 IU can be harmful, leading to the buildup of calcium in the blood, causing hypercalcemia. And some people with hypercalcemia may even experience nausea, kidney issues, or calcium deposits.

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