Researchers found link between oestrogen and protection of bones

A new study conducted at the Tokyo Medical and Dental University has revealed the associated between oestrogen and bone's protection.

By: IANS | | Published: March 24, 2019 3:56 pm

Osteoporosis is a condition in which bones become weak and prone to fractures. © Shutterstock

Researchers have found a new molecular link between oestrogen and bone ageing, which may eventually lead to new strategies to treat osteoporosis among post-menopausal women. Also Read - Dairy intake may not prevent osteoporosis in post-menopausal women, but lifestyle changes can

Also Read - Spending a little time in the sun every day will give you strong bones

Osteoporosis is a condition in which bones become weak and prone to fractures. Also Read - Osteoporosis: Here’s how you can prevent the condition

Women over 50 are at a high risk of developing osteoporosis, which may be due to the loss of oestrogen that occurs after menopause.

“Over the last few decades, we’ve learned that oestrogen plays an important role in maintaining a functional bone matrix,” said Tomoki Nakashima from the Tokyo Medical and Dental University (TMDU) in Japan.

However, how oestrogen does this, was not fully understood, the researchers said.

In the study, the researchers discovered a protein called Sema3A, which was found to maintain bone matrix, proteins and minerals in bone suggesting a relationship between oestrogen and Sema3A.

Further, the researchers found that blood serum levels of the protein Sema3A decreased in pre-menopausal women as they get older and dropped even more once they reach menopause.

In the study done on mice, the ovaries of mice were removed but it was found that the loss of oestrogen did not prevent their bones from deteriorating.

In addition, Sema3A was found to promote the survival of osteocytes — bone cells — in these mice.

“We believe that as women lose oestrogen with age and Sema3A levels drop, osteocytes begin to die and bone loses the ability to maintain its supportive structure,” Mikihito Hayashi from the varsity said.

Published : March 24, 2019 3:56 pm

Read Disclaimer

Automated way to detect eye surface cancer developed: Study

Smokers notice health warnings more on plain packs

About The health Site

TheHealthSite.com is India's largest health site with more than 40 lakh unique visitors per month. We focus on fitness, beauty, health, pregnancy and more.

Most popular health and wellness website in India in 2012 at the Website of the year awards.

health@corp.india.com

+91 – 22 – 6697 1234

91 – 22 – 2490 0302.

ZEE ENTERTAINMENT ENTERPRISES LTD, 18th floor, A-Wing, Marathon Futurex, N. M. Joshi Marg, Lower Parel, Mumbai, Maharashtra 400013.

We respect your privacy

Automated way to detect eye surface cancer developed: Study

Smokers notice health warnings more on plain packs

Dairy intake may not prevent osteoporosis in post-menopausal women, but lifestyle changes can

Vaginal inflammation and dryness can be painful: Deal with it naturally

Menopause affects sleep in women: Study

Spending a little time in the sun every day will give you strong bones

Osteoporosis: Here’s how you can prevent the condition

About The health Site

Useful Links