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Renal Replacement Therapy: What You Need To Know

What happens when your kidneys need a backup? Let's talk about renal replacement therapy

Renal Replacement Therapy: What You Need To Know
VerifiedVERIFIED By: Dr Nitin Shrivastava, Lead Consultant – Urologist, Manipal Hospital Gurugram

Written by Tavishi Dogra |Updated : March 20, 2025 12:14 PM IST

Kidney disease is a rapidly increasing issue across India, with an increasing number of cases each day being diagnosed. Changes in lifestyle patterns, an increase in hypertension and diabetes, as well as lack of knowledge about optimal kidney function are the contributing factors to this trend. One of the most noteworthy findings from a National Library of Medicine [https://pubmed.ncbi.nlm.nih.gov/39763170/] study is that chronic kidney disease (CKD) affects 13.24% of Indians, with rural India having 15.36% more affected than urban Indian. Renal replacement therapy (RRT) is a life-saving treatment for patients with impaired kidney function, which affects their ability to flush and store fluids.

What Is Renal Replacement Therapy?

In situations where the kidneys are unable to work without assistance, RRT is necessary. The treatment involves three main approaches: haemodialysis, peritoneal dialysis, and a kidney transplant. The treatment option depends on the patient's condition and the progression of kidney disease. Those with kidney disease in the early stages may not always choose RRT as the first course of action, but it is important during later stages of development to maintain good health.

  1. Haemodialysis: An external device is installed in this treatment to purify the blood and eliminate waste products and excess water from within the body. The medication is commonly given in a medical facility several times and might cause physical strain.
  2. Peritoneal Dialysis: A method that can be carried out at home, removes waste products from the blood and cleanses the abdomen's lining. While it's more flexible, it's important factor is the ongoing monitoring and compliance with protocols.
  3. Kidney Transplantation: A donor kidney is believed to be the most suitable long-term solution. Although it has a significant impact on quality of life, it needs an appropriate donor and ongoing immunosuppressant treatment to prevent organ rejection.

When Does Renal Replacement Therapy Become Necessary?

RRT is typically recommended when the kidney's function falls below a healthy level of 10-15%. Untreated toxins can cause serious health problems in the body so, immediate treatment is necessary to prevent further damage caused by symptoms such as severe fatigue, shortness of breath, and edema, which are indicative of kidney failure.

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Do's and Don'ts for kidney health:

Do's:

  1. It is recommended to eat a diet that is low in sodium and fat and contains plenty of fruits and vegetables.
  2. Regular exercise also helps to protect against any health determinants that may affect the kidneys.
  3. Regular kidney function tests is necessary in those with a high risk of kidney failure, early detection of abnormalities is often possible through regular testing.

Don'ts:

  1. Keep away from smoking and alcohol, as these have a detrimental effect on the arteries and kidneys.
  2. Limit ibuprofen and other painkillers as their long-term use can cause kidney damage.
  3. Seeking early medical guidance to reduce unusual urinary symptoms is recommended.
  4. Consuming foods high in protein puts the kidneys under additional strain so the consumption must be restricted.

When your kidneys can no longer function properly, renal replacement therapy (RRT) becomes a lifesaving option. Whether through dialysis or a kidney transplant, RRT helps remove waste, balance fluids, and maintain overall health.

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